May 8 (Reuters) - Wall Street's main indexes rose on Wednesday, boosted by megacap growth stocks and as corporate results rolled in, while investors awaited commentary from Federal Reserve policymakers for clues on the economy's health. .N

At 13:30 EDT, the Dow Jones Industrial Average .DJI was up 0.05% at 49,621.57. The S&P 500 .SPX was up 0.85% at 7,399.46, and the Nasdaq Composite .IXIC was up 1.56% at 26,209.39.

The top three S&P 500 .PG.INX percentage gainers:

** Akamai Technologies Inc AKAM.OQ, up 20.5%

** Intel Corp INTC.OQ, up 15.9%

** Moderna Inc MRNA.OQ, up 15.4%

The top three S&P 500 .PL.INX percentage losers:

** Mettler-toledo International Inc MTD.N, down 12.7%

** Motorola Solutions Inc MSI.N, down 11.1%

** Axon Enterprise Inc AXON.OQ, down 7.7%

The top three NYSE .PG.N percentage gainers:

** AMN Healthcare Services Inc AMN.N, up 21.6%

** Magnachip Semiconductor Corp MX.N, up 19.2%

** Callaway Golf Co CALY.N, up 18.9%

The top three NYSE .PL.N percentage losers:

** ESS Tech Inc GWH.N, down 35.5%

** Figs Inc FIGS.N, down 27.3%

** DXC Technology Co DXC.N, down 26.4%

The top three Nasdaq .PG.O percentage gainers:

** J-Star Holding Co Ltd YMAT.OQ, up 133.1%

** Innodata Inc INOD.OQ, up 85.3%

** Robo.ai Inc AIIO.OQ, up 75.7%

The top three Nasdaq .PL.O percentage losers:

** Republic Power Group Ltd RPGL.OQ, down 48.5%

** Smart Powerr Corp CREG.OQ, down 47.9%

** Forward Air Corp (Delaware) FWRD.OQ, down 44.1%

** News Corp NWSA.O:
BUZZ - ASX shares of News Corp hit three-month high on earnings beat nL4N41L0AZ

** CoreWeave Inc CRWV.O:
BUZZ - Falls after raising lower end of annual capex forecast nL4N41L0MZ

** Akamai Technologies Inc AKAM.O:
BUZZ - Surges as $1.8 billion cloud deal overshadows downbeat outlook nL4N41L0NY

** Monster Beverage Corp MNST.O:
BUZZ - Climbs after Q1 beat on strong demand for energy drinks nL6N41L0H9

** Trade Desk Inc TTD.O:
BUZZ - Slips on downbeat Q2 revenue forecast nL6N41L0IZ

** Biogen Inc BIIB.O:
BUZZ - Down after US FDA extends review of Alzheimer's drug nL4N41L0S2

** Koninklijke Philips NV PHG.N:
BUZZ - KBC ups Philips to 'buy' after results on track despite macro headwinds nL6N41L0G3

** Cloudflare Inc NET.N:
BUZZ - To cut 20% global workforce; shares fall nL6N41L0K3

** RXO Inc RXO.N:
BUZZ - TD Cowen raises RXO's PT on strengthening pricing trends nL4N41L0TF

** Fluor Corp FLR.N:
BUZZ - Falls as first-quarter profit misses estimates nL4N41L0VO

** Artiva Biotherapeutics Inc ARTV.O:
BUZZ - Jumps as cell therapy shows benefits in rheumatoid arthritis nL4N41L0VN

** Newmont Corp NEM.N:

** Harmony Gold Mining Co Ltd HMY.N:

** AngloGold Ashanti PLC AU.N:

** Sibanye Stillwater Ltd SBSW.N:

BUZZ - Gold miners rise as bullion heads for weekly gain nL4N41L0W8

** IREN Ltd IREN.O:
BUZZ - Surges on Nvidia's $2.1 bln AI investment nL6N41L0L7

** AAON Inc AAON.O:
BUZZ - Oppenheimer lifts AAON's PT, expects margin recovery on order rebound nL4N41L0X2

** Airbnb Inc ABNB.O:
BUZZ - Brokerages lift Airbnb's PT on 2026 forecast raise, growth initiatives nL4N41L0X5

** LifeStance Health Group Inc LFST.O:
BUZZ - Falls as PE backers offload in $285 mln secondary offering nL6N41L0N0

** Coinbase Global Inc COIN.O:
BUZZ - Slips after posting second straight quarterly loss nL6N41L0N6

** V2X Inc VVX.N:
BUZZ - Slips as PE firm divests stake in $149 mln secondary offering nL6N41L0NY

** Oshkosh Corp OSK.N:
BUZZ - Falls after quarterly profit misses estimates nL4N41L15H

** Tempus AI Inc TEM.O:
BUZZ - Rises after boosted $400 mln convertible bond offering nL6N41L0OC

** Microchip Technology Inc MCHP.O:
BUZZ - Rises on higher-than-expected Q1 forecast nL4N41L117

** PPL Corp PPL.N:
BUZZ - Gains on first-quarter profit beat nL4N41L12W

** Rocket Lab Corp RKLB.O:
BUZZ - Gains on upbeat quarterly revenue forecast nL4N41L12Z

** Wendy's Co WEN.O:
BUZZ - Rises after Q1 profit beat nL6N41L0PV

** MercadoLibre Inc MELI.O:
BUZZ - Falls as Q1 profit slips despite revenue jump nL4N41L17A

** Corning Inc GLW.N:
BUZZ - Shares rise on Nvidia factory funding nL4N41L14A

** Fidelity National Information Services Inc FIS.N:
BUZZ - Falls as weak Q2 profit forecast overshadows earnings beat nL4N41L16S

** Molina Healthcare Inc MOH.N:
BUZZ - Falls after forecasting decline in Medicaid enrollment nL4N41L16W

** Mettler-Toledo International Inc MTD.N:
BUZZ - Falls after modest quarterly forecast nL4N41L16Q

** Scorpio Tankers Inc STNG.N:
BUZZ - Eases after expanding convertible bond issue nL6N41L0S8

** BILL Holdings Inc BILL.N:
BUZZ - Gains after announcing job cuts, profit turnaround nL4N41L19S

** Moderna Inc MRNA.O:

BUZZ - Rises, poised for biggest daily gain in over three years nL4N41L1HT

Index RIC	Index name	Percent change %
.SPX	S&P 500	0.85
.SPLRCT	S&P 500 Information Technology	2.64
.SPLRCU	S&P 500 Utilities	-0.48
.SPLRCD	S&P 500 Consumer Discretionary	0.58
.SPLRCM	S&P 500 Materials	0.7
.SPLRCI	S&P 500 Industrials	-0.11
.SPLRCL	S&P 500 Communication Services (Sector)	-0.39
.SPSY	S&P 500 Financials	-0.5
.SPLRCR	S&P 500 Real Estate	0.59
.SPXHC	S&P 500 Health Care	-0.87
.SPLRCS	S&P 500 Consumer Staples	0.38
.SPNY	S&P 500 Energy	-0.43