Entrada Therapeutics posts corporate deck outlining Duchenne muscular dystrophy, DM1 clinical pipeline milestones
Entrada Therapeutics Inc
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- Entrada outlined a 2026 pipeline-heavy strategy in Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), targeting multiple clinical readouts.
- ENTR-601-44 DMD Cohort 1 met its safety and tolerability objective at 6 mg/kg; no serious adverse events or discontinuations reported.
- Cohort 1 showed functional gains versus placebo in Time to Rise and Time to Rise Velocity; open-label data expected by year-end 2026.
- ENTR-601-45 Cohort 1 data expected mid-2026; broader DMD filings for ENTR-601-50 and ENTR-601-51 planned following ongoing study reviews.
- Vertex-run VX-670 DM1 study moved into multiple-ascending-dose testing with results expected in H2 2026; partnership includes up to USD 485 million milestones.
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