• Evommune published a medical research presentation on proteomic profiling of dermal interstitial fluid in chronic inducible urticaria and chronic spontaneous urticaria.
• Lesional samples showed higher mast cell activation markers versus non-lesional skin, supporting mast cell involvement in both conditions.
• The analysis found enrichment of endogenous MRGPRX2 ligands in lesions, pointing to a shared MRGPRX2-driven disease mechanism.
• Proteomic signatures also indicated elevated inflammatory cytokines and chemokines in lesional skin, consistent across both patient groups.

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