EyePoint's late-stage eye drug trials to continue after safety panel review

EyePoint, Inc.
ريجينيرون
Ocular Therapeutix Inc

EyePoint, Inc.

EYPT

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Regeneron Pharmaceuticals, Inc.

REGN

0.00

Ocular Therapeutix Inc

OCUL

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- EyePoint EYPT.O said on Thursday an independent safety committee found no new concerns in two late-stage trials of its experimental eye disease drug Duravyu and recommended the studies continue unchanged.

  • The drug, Duravyu, is being tested to treat wet age-related macular degeneration, or wet AMD, a leading cause of vision loss in older adults that can cause blurred vision or a blind spot in the center of vision.

  • The independent safety committee completed its third scheduled review and recommended the studies continue without protocol changes.

  • EyePoint said topline data from the first study remain on track for mid-2026, with results from the second expected shortly after.

  • The studies have enrolled more than 900 patients and are evaluating Duravyu against Regeneron's REGN.O blockbuster eye drug, Eylea.

  • EyePoint said interim safety data showed a continued favorable safety profile, consistent with results seen in more than 190 patients across four earlier trials.

  • EyePoint said the main goal of the studies is to show Duravyu works about as well as Eylea in maintaining patients' vision at weeks 52 and 56.

  • The drug is also being tested in late-stage studies for diabetic macular edema, with data expected in the second half of 2027.

  • EyePoint in March filed a lawsuit against rival Ocular Therapeutix OCUL.O, accusing it of making misleading statements about EyePoint and Duravyu.