Molecular Partners doses first patients in Phase 1/2a trial of DLL3 Radio-DARPin MP0712

Molecular Partners AG Sponsored ADR

Molecular Partners AG Sponsored ADR

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  • Molecular Partners dosed first patients in a US Phase 1/2a trial of MP0712, a DLL3-targeting 212Pb Radio-DARPin partnered with Orano Med.
  • Cohort 1 recruitment completed; repeat dosing underway as the study evaluates safety across up to four dose levels.
  • Program uses a matched diagnostic-therapeutic approach, starting with 203Pb imaging and dosimetry to predict tumor uptake before treatment.
  • Initial data expected in 2026; broader safety and efficacy results targeted for 2027.


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