Monte Rosa publishes investor presentation on molecular glue degrader pipeline and Phase 2 plans

Monte Rosa Therapeutics, Inc.

Monte Rosa Therapeutics, Inc.

GLUE

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  • Monte Rosa outlined plans to start Phase 2 trials in 2026 for three molecular glue degrader programs, including VAV1 degrader MRT-6160, NEK7 degrader MRT-8102, and GSPT1 degrader MRT-2359.
  • Pipeline update flagged Phase 2 initiation for MRT-8102 in Q3 2026, with Phase 1 data for MRT-2359 followed by Phase 2 initiation in H2 2026.
  • Additional wholly owned IND submissions targeted for H2 2026, including CCNE1 MGD, with further INDs anticipated over next two years.
  • Collaboration economics highlighted USD 350 million received in collaboration payments over last three years, with potential for more than USD 400 million over next 24 months.
  • Balance sheet commentary pointed to cash runway into 2029.


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