Novartis says rare muscle disease drug shows promise in early trial
Novan, Inc. NOVN | 0.00 |
June 11 (Reuters) - Novartis NOVN.S said on Thursday an experimental drug, which it acquired as part of its $12 billion takeover of Avidity, showed promise in an early-to-mid-stage study in patients with a type of genetic muscle disorder characterized by slowly progressive muscle weakness.
The Swiss drugmaker said the drug, known as del-brax, lowered two blood markers linked to the disease and showed reduced signs of muscle damage in patients with facioscapulohumeral muscular dystrophy.
Novartis said the drug shows potential to become the first disease-modifying treatment for FSHD, which can cause weakness in the face, shoulders, arms and other muscles.
The company estimates it affects about 45,000 to 87,000 people in the U.S. and EU.
The drug's safety profile was consistent with previous results, the company said.
Novartis plans to discuss the data with health regulators around the world, while a late-stage study of the drug is currently enrolling patients.
