• Director Bryan Giraudo reported sales of 47,130 Protagonist Therapeutics common shares on May 7-8, including 36,000 shares at USD 100.14 weighted average and 5,130 shares at USD 100.
• He also exercised stock options for 36,000 shares on May 7 at USD 6.45 to USD 6.98 per share.
• Directly held common shares stood at 12,695 following transactions.
• Bryan & Courtney Giraudo Trust reported 0 shares following separate sales of 12,000 shares on May 7 at USD 100.07 and 6,000 shares on May 8 at USD 100.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Protagonist Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001104659-26-058860), on May 11, 2026, and is solely responsible for the information contained therein.