• Septerna Chief People Officer Samira Shaikhly reported selling 5,935 shares on June 1, 2026 at $27.78 to $29.66.
• She also exercised stock options the same day for 5,935 shares at $1.55 to $2.76 per share.
• Her directly held common stock position fell to 793 shares following the transactions.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001193125-26-255997), on June 03, 2026, and is solely responsible for the information contained therein.