Alnylam, Inceptive sign up to $2 billion AI drug discovery deal

Alnylam Pharmaceuticals, Inc

Alnylam Pharmaceuticals, Inc

ALNY

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- Alnylam Pharmaceuticals ALNY.O said on Wednesday it has teamed up with artificial-intelligence biotech Inceptive in a deal worth up to $2 billion to use AI to speed up discovery of RNA-based medicines.

  • Drugmaker Alnylam will pay $30 million upfront, including cash and an equity investment in privately held Inceptive, with additional payments tied to pre-clinical, regulatory and sales milestones.

  • The partnership combines Alnylam's RNAi drug platform and more than 20 years of data with Inceptive's AI models to help design and select drug candidates faster.

  • Inceptive focuses on developing models for sequence-based medicines such as RNAi therapeutics.

  • RNAi medicines work by blocking specific disease-related genes, helping reduce harmful proteins in the body.

  • Alnylam said the collaboration supports its Alnylam 2030 strategy to expand its drug pipeline.

  • Inceptive's foundation model learns the patterns underlying biology and hence can adapt to diverse therapeutic modalities without retraining.

  • The collaboration aims to help Alnylam prioritize the most promising molecules and improve experimental productivity.

  • Alnylam shares were up more than 2% in extended trading.