Alto Neuroscience says Phase 2 ALTO-101 schizophrenia cognition study misses primary endpoint

Alto Neuroscience, Inc.

Alto Neuroscience, Inc.

ANRO

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  • Alto Neuroscience reported topline Phase 2 proof-of-concept results for ALTO-101 in cognitive impairment associated with schizophrenia.
  • Study failed to meet primary endpoints versus placebo, limiting near-term path to independent development in this indication.
  • More detailed results will be presented at a future medical conference.
  • Strategy shifts toward seeking partners for a once-daily modified-release oral ALTO-101 formulation developed to improve tolerability.
  • Pipeline focus moves to lead program ALTO-207, with Phase 2b initiation targeted for 1H 2026.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alto Neuroscience Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 202604011630BIZWIRE_USPR_____20260401_BW931058) on April 01, 2026, and is solely responsible for the information contained therein.