The expansion will increase BeOne's production capacity to manufacture its medicines and is expected to create approximately 120 new full-time jobs. The investment supports the continued advancement of BeOne's deep oncology pipeline of more than 35 clinical and commercial-stage assets.

Aaron Rosenberg, Chief Financial Officer, BeOne Medicines, said:

"Today's announcement reflects BeOne's commitment to strengthening U.S. manufacturing and expanding access to innovative medicines for patients with cancer. We appreciate the federal tax policies advanced by the President that encourage investment in biopharmaceutical production, alongside the Next New Jersey Manufacturing Program and the Governor’s efforts to support advanced manufacturing and high-quality job creation. Together, these efforts create an environment for long-term growth, and we are proud to continue expanding our global footprint in support of patients."

Expanding manufacturing capacity

With this expansion, BeOne's Princeton West Innovation Campus will become a fully integrated, multi-platform manufacturing site, combining existing biologics production with new small molecule drug product capabilities under one roof. The expansion involves construction of a new three-story, 145,000-square-foot building adjacent to BeOne's existing Hopewell facilities, bringing the total campus footprint to approximately 545,000 square feet. The new building will house drug product manufacturing and packaging operations that strengthen BeOne's production and supply chain capabilities to support its growing hematology portfolio and pipeline, alongside quality control laboratories, office space, and capacity reserved for future growth. The expanded site will also provide additional flexibility to support strategic collaborations with partners and advance BeOne's global development superhighway.

Expansion highlights include:

Total capital investment: $300 million, bringing total Hopewell investment to more than $1 billion
New full-time positions: Approximately 120
New construction: Approximately 145,000 square feet; expanded facility anticipated to be fully operational in 2029
Total campus size post-expansion: Approximately 545,000 square feet
Hopewell site headcount: Approximately 240 by the end of 2029
BeOne's Princeton West Innovation Campus

Opened in July 2024 following an initial investment of $800 million, the latest $300 million expansion brings total investment at the Princeton West Innovation Campus to more than $1 billion. As BeOne's flagship U.S. manufacturing and clinical R&D hub, the campus also supports clinical and commercial-stage biologics manufacturing for the Company's solid tumor portfolio. The 42-acre site features more than 1 million square feet of developable real estate for future growth.

Accelerating BeOne's global development superhighway

The U.S. expansion strengthens BeOne’s global development superhighway, the company’s fully internal platform of clinical, regulatory, and manufacturing capabilities. This strategically advantaged model combines one of the industry’s largest oncology research teams with nearly 6,000 clinical development and manufacturing colleagues, helping reduce the cost and time required to develop new medicines for cancer patients around the world. The added capacity will support pipeline programs across multiple blood cancers, as well as breast, gynecologic, lung, liver, gastrointestinal, and other tumor types. These programs span multiple innovative modalities, including small molecules, biologics, targeted protein degraders, multispecific antibodies, and antibody drug conjugates.

BeOne in the United States

BeOne is domiciled in Switzerland and employs over 12,000 colleagues across six continents, including more than 2,000 in the U.S. In 2025, BeOne generated nearly $2 billion in direct U.S. economic impact and invested approximately $1 billion in U.S. R&D. The company is conducting 93 clinical trials across 45 states and one territory at approximately 1,100 clinical trial sites, supported by more than 650 investigators. BeOne Medicines has delivered its life-changing cancer therapies to more than 2 million patients globally.