CervoMed completes enrollment in Phase 2a neflamapimod trial for nonfluent primary progressive aphasia
CervoMed Inc. CRVO | 0.00 |
- CervoMed completed enrollment in a Phase 2a study of neflamapimod in nonfluent variant primary progressive aphasia, a frontotemporal dementia subtype.
- Trial enrolled 25 participants on oral dosing for 24 weeks, testing 40 mg three times daily or 80 mg twice daily regimens.
- Interim biomarker data are slated for presentation at the CTAD conference in November 2026.
- First biomarker readout is expected in early Q4 2026; first clinical data are targeted for Q1 2027.
- Preclinical findings in Nature Neuroscience linked p38α inhibition to improved axonal transport in tau-mutation mouse models, supporting the program’s rationale.
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