CSL Enters Into An Exclusive Licensing Agreement With Eli Lilly, Granting Certain Rights To Develop And Commercialize Clazakizumab For An Upfront Payment Of $100M And Potential Milestone Payments, As Well As Sales-based Royalties

Eli Lilly and Company -1.89%
CSL LTD +2.61%

Eli Lilly and Company

LLY

905.03

-1.89%

CSL LTD

CSLLY

25.40

+2.61%

  • Under the terms of the agreement, CSL will retain exclusive rights to develop and commercialise clazakizumab for the prevention of cardiovascular events in patients with end-stage kidney disease (ESKD). 
  • CSL is advancing the ongoing POSIBIL 6ESKD Phase 3 clinical trial (NCT05485961), which is evaluating the efficacy and safety of clazakizumab in patients with ESKD on dialysis at risk for major cardiovascular events. 
  • Under the terms of the agreement, CSL will retain exclusive rights to develop and commercialise clazakizumab for the prevention of cardiovascular events in patients with ESKD. 
  • Lilly will explore the development, global regulatory approval, and commercialisation of clazakizumab in additional indications. CSL will receive an upfront payment of $100 million and be eligible to receive potential clinical, regulatory and commercial milestone payments, as well as royalties on global net sales
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