Disc Medicine says DISC-0974 shows durable anemia responses in RALLY-MF Phase 2 myelofibrosis trial data update at ASCO 2026

Disc Medicine, Inc.

Disc Medicine, Inc.

IRON

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  • Disc Medicine presented updated Phase 2 RALLY-MF data for DISC-0974 in myelofibrosis-related anemia at the 2026 ASCO meeting.
  • Treatment produced durable improvements in anemia across patient subgroups, including those needing transfusions at baseline.
  • Responses were consistent in patients on JAK inhibitors, supporting use alongside standard myelofibrosis therapy.
  • The safety profile looked manageable, with limited treatment-related side effects reported.
  • Additional RALLY-MF data are scheduled for Q4 2026, ahead of an expected end-of-Phase 2 FDA meeting by year-end.


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