Erasca releases ERAS-0015 preliminary Phase 1 data update presentation

Erasca, Inc.

Erasca, Inc.

ERAS

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  • Erasca released a preliminary Phase 1 update for ERAS-0015 from the AURORAS-1 first-in-human trial.
  • In 2L+ KRAS G12X pancreatic ductal adenocarcinoma, uORR reached 57% at 32 mg once daily (4/7) through May 25, 2026.
  • Disease control rate was 100% at 32 mg (7/7) through May 25, 2026; 24 mg showed 25% uORR (2/8).
  • In colorectal cancer, the ERAS-0015 16 mg once-daily combination with panitumumab showed no DLTs; 24 mg cohort enrolling as of July 6, 2026.
  • Milestones target monotherapy expansion initiation in 2H26; combination dose-escalation data, including panitumumab, in 1H27.


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