Filana Therapeutics posts Eilat XVIII scientific presentation on simufilam in TSC seizures

Filana Therapeutics, Inc.

Filana Therapeutics, Inc.

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  • Filana Therapeutics published a scientific conference presentation outlining simufilam development for tuberous sclerosis complex-associated seizures.
  • Program targets filamin A modulation; presentation cites animal-model data showing reduced seizure activity in TSC and focal cortical dysplasia type II models.
  • Document highlights prior safety database in Alzheimer’s trials, covering more than 1,900 patients across two placebo-controlled studies with no emerging safety signals.
  • Preliminary Phase 2 proof-of-concept design described for ages 12-50, comparing 100 mg BID vs 200 mg BID with seizure-count reduction as a key endpoint.


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