Fractyl Health publishes REVEAL-1 one-year Revita data presentation on post-GLP-1 weight maintenance

Fractyl Health, Inc.

Fractyl Health, Inc.

GUTS

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  • Fractyl Health published one-year open-label REVEAL-1 results evaluating its investigational Revita procedure for post-GLP-1 weight maintenance.
  • Completers retained about 78.3% of GLP-1 weight loss at 52 weeks; average weight change was +5.3% from post-GLP-1 baseline.
  • Weight regain was about 22% versus 60%-65% projected in historical GLP-1 withdrawal studies.
  • Five of 15 completers lost additional weight through 52 weeks off GLP-1 therapy.
  • Safety update showed no device- or procedure-related serious adverse events through 12 months.


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