Genmab, AbbVie clarify primary endpoints in Phase 3 EPCORE DLBCL-1 trial

Genmab A/S
AbbVie, Inc.

Genmab A/S

GMAB

0.00

AbbVie, Inc.

ABBV

0.00
  • Genmab issued a clarification correcting how primary endpoints were described for the Phase 3 EPCORE DLBCL-1 epcoritamab trial.
  • In the U.S., overall survival was the sole primary endpoint; the study missed it, with no statistically significant overall survival improvement.
  • The trial uses region-specific primary endpoints, creating a mismatch with earlier topline messaging; additional results are slated for journal submission.


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