Headlands Research phase 3 study backs coadministering mRESVIA with high-dose flu shot in seniors

Moderna

Moderna

MRNA

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  • Headlands Research highlighted results from a phase 3 study of coadministration of Moderna mRNA-1345 RSV vaccine mRESVIA with a high-dose quadrivalent seasonal influenza vaccine in adults aged 65 and older, with results already reported in a newly published paper.
  • Coadministration was generally well tolerated, supporting a simpler vaccination approach for older adults during respiratory virus season.
  • Study showed strong immune responses against influenza strains, supporting expected protection from flu alongside RSV vaccination.
  • Data also supported maintained protection against RSV-related lower respiratory tract disease, reducing concern that paired dosing could dilute RSV benefit.
  • Findings could support more convenient vaccination strategies, which may help improve uptake in a key commercial age group.


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