iBio says single-dose IBIO-610 achieves 98% Activin E inhibition through eight weeks in obese primate study

iBio, Inc.

iBio, Inc.

IBIO

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  • iBio reported obese non-human primate data for IBIO-610, an Activin E antibody candidate, showing near-complete inhibition through eight weeks after one dose.
  • Active Activin E fell 98% at week 4, 97% at week 8 versus baseline; both timepoints were below the assay’s detection limit.
  • In combination with semaglutide, IBIO-610 increased visceral and total fat loss, cutting lean mass loss 73% versus semaglutide alone.
  • Results support a low-frequency dosing profile; the full dataset is slated for presentation at EASD on Oct. 1, 2026.


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