Innate Pharma publishes corporate presentation on three lead oncology assets lacutamab, IPH4502, monalizumab

  • Innate Pharma investor deck centered on three lead oncology programs, with lacutamab in cutaneous T-cell lymphoma, IPH4502 in solid tumors, monalizumab in non-small cell lung cancer.
  • Lacutamab Phase 2 TELLOMAK in Sézary syndrome post-mogamulizumab reported global ORR 42.9% with median duration of response 25.6 months; median PFS 8.3 months.
  • Company outlined plan to start TELLOMAK-3 Phase 3 in H2 2026, positioning it as confirmatory trial in Sézary syndrome versus romidepsin with primary endpoint PFS by blinded independent central review; potential accelerated approval in 2027 shown on regulatory timeline.
  • IPH4502 Phase 1 program cited preliminary anti-tumor activity in heavily pre-treated advanced solid tumors, including urothelial cancer post-enfortumab vedotin, with favorable safety profile to date.
  • Monalizumab PACIFIC-9 Phase 3 in unresectable NSCLC has completed enrollment, with Phase 3 readout targeted for H2 2026; deck reiterated up to USD 825 million potential milestones, 50% EU profit share, double-digit royalties in US and rest of world.


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