Ionis And AstraZeneca's CARDIO-TTRansform Phase 3 Trial Of Eplontersen Misses Primary Endpoint In Transthyretin-Mediated Amyloid Cardiomyopathy Patients Compared With Placebo

Ionis Pharmaceuticals, Inc.
AstraZeneca PLC

Ionis Pharmaceuticals, Inc.

IONS

0.00

AstraZeneca PLC

AZN

0.00
  • Study missed primary endpoint of composite outcome of cardiovascular (CV) mortality and recurrent CV events; in a pre-specified subgroup analysis, a nominally significant result was observed with eplontersen monotherapy 
  • Favorable safety profile consistent with previous results
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