Ionis doses first patient in Phase 1-2 trial of ION337 for Dravet syndrome

Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.

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  • Ionis Pharmaceuticals dosed the first participant in the Phase 1-2 ASCEND trial of ION337 for Dravet syndrome.
  • Open-label study tests safety in children ages 2-12; includes a 6-month single ascending dose phase.
  • Program then moves to a 24-month multiple ascending dose phase with intrathecal dosing every 6 months.


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