Ionis Pharmaceuticals shares are trading lower after the announcement that it and AstraZeneca's CARDIO-TTRansform Phase III trial of eplontersen missed the primary endpoint of the composite outcome of cardiovascular mortality and recurrent CV clin...

Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.

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Ionis Pharmaceuticals shares are trading lower after the announcement that it and AstraZeneca's CARDIO-TTRansform Phase III trial of eplontersen missed the primary endpoint of the composite outcome of cardiovascular mortality and recurrent CV clinical events up to 140 weeks compared with placebo,