MeiraGTx publishes corporate deck outlining late-stage gene therapy pipeline, manufacturing platform

MEIRAGTX HOLDINGS PLC

MEIRAGTX HOLDINGS PLC

MGTX

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  • MeiraGTx highlighted four late-stage gene therapy programs, led by AAV-AQP1 in pivotal Phase 2 for radiation-induced xerostomia with potential BLA filing early 2027.
  • X-linked retinitis pigmentosa program completed Phase 3, described as BLA and MAA ready, with process performance qualification reported complete.
  • AAV-GAD for Parkinson’s disease positioned as Phase 3 ready, with a potential BLA filing in 2028, supported by sham-controlled trial data.
  • Ophthalmology collaboration with Eli Lilly outlined, including USD 75 million upfront cash, up to USD 135 million near-term AAV-AIPL1 milestones, royalties.
  • Hologen AI transaction detailed, including USD 200 million upfront cash, a JV backed by USD 230 million committed capital to fund AAV-GAD through commercialization.


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