Moderna And Merck Present 5-Year Data For Intismeran Autogene in Combination With KEYTRUDA In Patients With High-Risk Stage III/IV Melanoma

Merck
Moderna

Merck

MRK

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Moderna

MRNA

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At a median 5-year (60.3 months) planned follow-up of the Phase 2b KEYNOTE-942/mRNA-4157-P201 study, intismeran autogene in combination with KEYTRUDA demonstrated a 49% reduction in the risk of recurrence or death and a 59% reduction in the risk of distant metastasis or death compared to KEYTRUDA alone

Intismeran autogene in combination with KEYTRUDA demonstrated an encouraging trend toward overall survival in an exploratory analysis compared to KEYTRUDA alone (HR=0.471; [95% CI, 0.165-1.345])

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