Ollin raises $330 million to fund late-stage eye disease drug trials

By Kunal Das and Sneha S K

- Texas-based biotech Ollin Biosciences said on Wednesday it has raised $330 million in its latest funding round to advance late-stage studies of its experimental eye disease drug.

  • Ollin said the funds will support late-stage global studies of its drug, OLN324, to treat diabetic macular edema (DME) and wet age-related macular degeneration (AMD), two leading causes of vision loss.

  • The funding will also help move OLN102, an experimental drug for thyroid eye disease and Graves' disease, into human testing this year.

  • The company plans to start the trials for OLN324 in the second half of 2026.

  • The Series B funding round was oversubscribed and was co-led by TCGX and ARCH Venture Partners, with participation from investors including a16z Bio+Health, Blackstone Multi-Asset Investing, and T. Rowe Price Investment Management.

  • Ollin did not disclose the valuation at which the funds were raised.

  • The company has arrived at a "really compelling set of study designs" that support potential approval and also highlight potential for improved treatment outcomes, CEO Jason Ehrlich told Reuters.

  • OLN324 is an antibody that targets two key disease signals to treat abnormal blood vessel growth and leakage in the eye.

  • In a recent early-stage head-to-head study, the drug showed faster and greater improvements in eye structure and greater vision gains in both DME and wet AMD than Roche's ROPC.S Vabysmo, Ollin said.

  • Both drugs are being developed in collaboration with China-based biotech firms: OLN324 with Innovent Biologics 1801.HK and OLN102 with VelaVigo, the company said.

  • Ollin launched with an initial $100 million financing led by ARCH Venture Partners, Mubadala Capital and Monograph Capital last year.