Sana says NEJM publishes 14-month data supporting hypoimmune islet transplant in type 1 diabetes without immunosuppression

Sana Biotechnology, Inc.

Sana Biotechnology, Inc.

SANA

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  • Sana Biotechnology highlighted NEJM publication of 14-month follow-up data for UP421 hypoimmune-modified islet cell transplant in type 1 diabetes.
  • Study reported continued insulin production without immunosuppression, with circulating C-peptide present at month 14 versus undetectable at baseline.
  • No safety issues were identified; imaging at 52 weeks showed islet cells at the forearm muscle transplant site.
  • Sana expects to file an IND and start a Phase 1/2 trial as early as this year for SC451, a stem cell-derived HIP-modified therapy.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sana Biotechnology Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202607130800PRIMZONEFULLFEED9760965) on July 13, 2026, and is solely responsible for the information contained therein.