Silexion Therapeutics Announces Data From Its Current Translational Immuno-Oncology Trial Of SIL204 Shows Increase In Surface Expression Of Major Histocompatibility Complex Class I

Biomotion Sciences. Ordinary Shares

Biomotion Sciences. Ordinary Shares

SLXN

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Silexion Therapeutics Corp. (NASDAQ:SLXN) ("Silexion" or the "Company"), a clinical-stage biotechnology company pioneering RNA interference (RNAi) therapies for KRAS-driven cancers, today announced positive preclinical findings from an ongoing translational immuno-oncology study evaluating its lead candidate, SIL204, in human KRAS-mutated pancreatic cancer cells. The study demonstrated a statistically significant increase in surface expression of major histocompatibility complex class I (MHC-I), also known as HLA-ABC, following treatment with SIL204 in human pancreatic cancer cells harboring the KRAS G12R mutation, as measured by flow cytometry.

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