Turn Therapeutics posts corporate presentation on GX-03 topical immunomodulator for atopic dermatitis

Turn Therapeutics Inc.

Turn Therapeutics Inc.

TTRX

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  • Turn Therapeutics highlighted lead topical candidate GX-03, a non-systemic IL-36/IL-31 inhibitor program for moderate-to-severe atopic dermatitis, with a Phase 2 randomized controlled trial underway and topline data expected mid-2026.
  • Phase 2 design calls for about 120 patients, with an adaptive option to expand to 200; primary endpoint is change in IGA score versus vehicle at week 8.
  • Presentation cited more than 200,000 patients previously receiving GX-03 in other cleared uses, with zero reported adverse events, including a 53-patient RIPT study that reported no adverse reactions across more than 580 applications.
  • Management outlined a development path targeting Phase 3 initiation in 2027, with a planned GX-03 launch in 2029, subject to trial outcomes and capital availability.
  • Turn also positioned PermaFusion, an emulsifier-free, oil-based delivery platform, as a proprietary approach to improve topical penetration across skin, nails, and mucous membranes.


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