UPDATE 1-Allogene's blood cancer therapy delays cancer relapse in mid-stage study

Allogene Therapeutics, Inc.

Allogene Therapeutics, Inc.

ALLO

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- Allogene Therapeutics ALLO.O said on Monday that interim data from a mid-stage study showed its experimental off-the-shelf CAR-T therapy reduced the risk of cancer relapse in patients with blood cancer.

The company was testing its allogeneic, or "off-the-shelf," CAR-T therapy in patients with a type of blood cancer whose disease remained detectable even after their initial round of standard treatment.

The CAR-T therapy, named cema-cel, utilizes white blood cells, specifically T-cells, from healthy donors.

These cells are re-engineered to create cancer-fighting immune cells. This treatment is pre-manufactured and readily available for administration to patients.

This differs from currently approved CAR-T therapies, which require collecting and genetically modifying a patient's own immune cells, with reinfusion occurring weeks later.