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May 6 (Reuters) - Oil and gas producer APA APA.O beat Wall Street estimates for first-quarter profit on Wednesday, as stronger oil prices helped offset a decline in output.

The reported quarter was marked by macro uncertainty and extreme volatility in global oil prices as the U.S.-Israeli war in Iran disrupted supply routes and damaged key energy infrastructure in the Middle East.

Most of APA's operations are based in the U.S., followed by Egypt, the North Sea and Suriname. The energy company is still exposed to changes in commodity prices due to geopolitical events.

APA said its realized price for each barrel of oil produced rose to $78.69 during the first quarter, from $73.73 per barrel in the year-ago period.

The Houston, Texas-based company posted an adjusted profit of $1.38 per share for the three months ended March 31, compared with analysts' average estimate of $1.12, according to data compiled by LSEG.