AstraZeneca's Baxfendy Wins FDA Approval As First-In-Class Aldosterone Synthase Inhibitor For Uncontrolled Hypertension

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Approval based on BaxHTN Phase III results showing statistically significant and clinically meaningful reduction in systolic blood pressure in patients with uncontrolled or resistant hypertension.  Baxfendy 2mg lowered systolic blood pressure by 15.7 mmHg (9.8 mmHg placebo-adjusted) from baseline in the BaxHTN trial.