MetaVia says Phase 1 trial shows DA-1726 cuts mean body weight up to 9.1% at 48 mg dose

MetaVia Inc.

MetaVia Inc.

MTVA

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  • MetaVia presented higher-dose Phase 1 results for obesity drug candidate DA-1726 at EASL 2026 on May 27.
  • The study showed meaningful, continuing weight loss with no sign of an early plateau during follow-up.
  • Safety profile looked manageable, with mostly mild-to-moderate gastrointestinal side effects and no treatment-related dropouts reported.
  • Exploratory liver scans suggested early improvements consistent with potential use in obesity-related liver disease, including MASH.
  • Ongoing Phase 1 titration studies are testing longer treatment and higher-dose strategies to support next-stage development.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Metavia Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: 202605270831PR_NEWS_USPR_____NY67791) on May 27, 2026, and is solely responsible for the information contained therein.