Nurix reports 22.1-month median PFS in Phase 1a trial of BTK degrader bexobrutideg for relapsed/refractory CLL/SLL
Nurix Therapeutics
Nurix Therapeutics NRIX | 0.00 |
- Nurix flagged updated Phase 1a/b results for bexobrutideg, a BTK degrader for CLL/SLL, scheduled for presentation at the 2026 EHA Congress.
- Heavily pretreated relapsed or refractory patients showed durable responses, supporting continued development despite prior exposure to multiple standard therapies.
- Earlier-line cohorts showed strong anti-tumor activity, including patients who had progressed on a BTK inhibitor but had not used a BCL2 inhibitor.
- The safety profile remained broadly consistent with prior disclosures, with tolerability supporting longer treatment duration and expansion into broader studies.
- Nurix said the readout underpins plans for a broad Phase 3 monotherapy program, with combination regimens also under evaluation alongside a Roche collaboration.
Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Nurix Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202606110700PRIMZONEFULLFEED9735379) on June 11, 2026, and is solely responsible for the information contained therein.
